| 1. Round | 29/07/2017 | San Luis | - | Huachipato | 2:0 |  |
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| 2. Round | 06/08/2017 | Everton | - | San Luis | 4:0 | |
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| 3. Round | 13/08/2017 | San Luis | - | Universidad de Chile | 2:0 | |
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| 4. Round | 19/08/2017 | Unión Española | - | San Luis | 1:0 | |
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| 5. Round | 26/08/2017 | Palestino | - | San Luis | 1:3 | |
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| 7. Round | 23/09/2017 | Colo-Colo | - | San Luis | 3:0 | |
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| 8. Round | 01/10/2017 | San Luis | - | O'Higgins | 2:1 | ||||
| 10. Round | 22/10/2017 | San Luis | - | Antofagasta | 1:3 | ||||
| 11. Round | 29/10/2017 | Curicó Unido | - | San Luis | 1:0 |  |
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| 13. Round | 24/11/2017 | San Luis | - | Universidad de Concepción | 0:0 | ||||
| 14. Round | 02/12/2017 | Deportes Iquique | - | San Luis | 2:1 | |
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| 15. Round | 10/12/2017 | San Luis | - | Audax Italiano | 1:1 |  |
Argentina