| 4. Round | 28/08/2021 | AS Monaco B | - | Hyères FC | 0:1 | ||||
| 5. Round | 04/09/2021 | Lyon-La Duchère | - | AS Monaco B | 0:2 | ||||
| 6. Round | 11/09/2021 | SC Toulon | - | AS Monaco B | 3:0 | ||||
| 8. Round | 25/09/2021 | GFA Rumilly Vallières | - | AS Monaco B | 1:2 | ||||
| 14. Round | 11/12/2021 | Olympique Marseille B | - | AS Monaco B | 0:1 |  |
|||
| 15. Round | 15/01/2022 | AS Monaco B | - | Marignane Gignac FC | 0:1 | ||||
| 17. Round | 05/02/2022 | AS Monaco B | - | Louhans-Cuiseaux | 1:1 | ||||
| 19. Round | 19/02/2022 | AS Monaco B | - | Lyon-La Duchère | 2:2 | ||||
| 21. Round | 12/03/2022 | FC Martigues | - | AS Monaco B | 1:2 | |
|||
| 22. Round | 19/03/2022 | AS Monaco B | - | GFA Rumilly Vallières | 2:2 | ||||
| 30. Round | 28/05/2022 | AS Monaco B | - | Olympique Lyonnais B | 4:1 |
France