| 12. Round | 09/08/2022 | Tigre | - | Rosario Central | 3:1 | ||||
| 13. Round | 13/08/2022 | Rosario Central | - | Barracas Central | 3:1 | ||||
| 15. Round | 22/08/2022 | Rosario Central | - | Banfield | 0:1 | ||||
| 17. Round | 03/09/2022 | Rosario Central | - | Talleres de Córdoba | 1:0 |  |
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| 19. Round | 15/09/2022 | Rosario Central | - | Estudiantes | 1:1 | ||||
| 20. Round | 20/09/2022 | Patronato de Paraná | - | Rosario Central | 0:0 | ||||
| 22. Round | 01/10/2022 | Racing Club | - | Rosario Central | 4:3 | |
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| 23. Round | 04/10/2022 | Rosario Central | - | Unión de Santa Fe | 1:1 |
Argentina