| 1. Round | 19/07/2021 | Central Córdoba SdE | - | Banfield | 1:1 | ||||
| 2. Round | 24/07/2021 | San Lorenzo | - | Central Córdoba SdE | 1:0 |  |
|||
| 3. Round | 29/07/2021 | Central Córdoba SdE | - | Talleres de Córdoba | 2:1 | ||||
| 4. Round | 02/08/2021 | Argentinos Juniors | - | Central Córdoba SdE | 1:1 | ||||
| 5. Round | 10/08/2021 | Central Córdoba SdE | - | Estudiantes | 1:2 | ||||
| 6. Round | 15/08/2021 | Patronato de Paraná | - | Central Córdoba SdE | 1:0 | ||||
| 7. Round | 21/08/2021 | Central Córdoba SdE | - | Platense | 2:2 | ||||
| 11. Round | 14/09/2021 | Central Córdoba SdE | - | Atlético Tucumán | 2:0 | ||||
| 12. Round | 19/09/2021 | Colón de Santa Fe | - | Central Córdoba SdE | 1:0 | ||||
| 13. Round | 26/09/2021 | Central Córdoba SdE | - | River Plate | 1:3 | ||||
| 14. Round | 02/10/2021 | Lanús | - | Central Córdoba SdE | 2:1 | ||||
| 15. Round | 08/10/2021 | Central Córdoba SdE | - | Huracán | 1:2 | ||||
| 16. Round | 15/10/2021 | Godoy Cruz | - | Central Córdoba SdE | 0:0 | ||||
| 17. Round | 20/10/2021 | Central Córdoba SdE | - | Vélez Sarsfield | 1:2 |
Argentina