| 1. Round | 07/06/2022 | Argentinos Juniors | - | Aldosivi | 2:1 | ||||
| 2. Round | 11/06/2022 | Sarmiento de Junín | - | Argentinos Juniors | 1:0 | ||||
| 8. Round | 16/07/2022 | Barracas Central | - | Argentinos Juniors | 1:3 |  |
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| 14. Round | 19/08/2022 | Argentinos Juniors | - | Estudiantes | 1:0 | ||||
| 17. Round | 03/09/2022 | Racing Club | - | Argentinos Juniors | 1:0 | ||||
| 18. Round | 09/09/2022 | Argentinos Juniors | - | Rosario Central | 2:1 | |
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| 19. Round | 15/09/2022 | Defensa y Justicia | - | Argentinos Juniors | 2:1 | |
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| 25. Round | 13/10/2022 | Godoy Cruz | - | Argentinos Juniors | 0:0 |
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