| 3. Round | 21/08/2021 | Marignane Gignac FC | - | AS Saint-Priest | 0:1 | ||||
| 4. Round | 28/08/2021 | Étoile FC | - | Marignane Gignac FC | 2:0 |  |
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| 6. Round | 11/09/2021 | Aubagne FC | - | Marignane Gignac FC | 3:0 | ||||
| 7. Round | 18/09/2021 | Marignane Gignac FC | - | Jura Sud | 1:0 |  |
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| 8. Round | 25/09/2021 | Olympique Marseille B | - | Marignane Gignac FC | 2:3 | |
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| 9. Round | 09/10/2021 | Marignane Gignac FC | - | SC Toulon | 0:1 | ||||
| 10. Round | 23/10/2021 | Marignane Gignac FC | - | Olympique Lyonnais B | 4:0 |  |
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| 11. Round | 06/11/2021 | RC Grasse | - | Marignane Gignac FC | 2:0 | ||||
| 17. Round | 05/02/2022 | AS Saint-Priest | - | Marignane Gignac FC | 0:0 | ||||
| 22. Round | 19/03/2022 | Marignane Gignac FC | - | Olympique Marseille B | 4:1 | ||||
| 23. Round | 26/03/2022 | SC Toulon | - | Marignane Gignac FC | 1:2 | ||||
| 24. Round | 09/04/2022 | Olympique Lyonnais B | - | Marignane Gignac FC | 3:1 | ||||
| 26. Round | 23/04/2022 | Louhans-Cuiseaux | - | Marignane Gignac FC | 0:0 |
Algeria