| 17. Round | 05/02/2022 | AS Saint-Priest | - | Marignane Gignac FC | 0:0 | ||||
| 18. Round | 12/02/2022 | Olympique Lyonnais B | - | AS Saint-Priest | 0:0 | ||||
| 19. Round | 19/02/2022 | AS Saint-Priest | - | RC Grasse | 3:3 |  |
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| 20. Round | 05/03/2022 | Louhans-Cuiseaux | - | AS Saint-Priest | 0:1 | |
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| 21. Round | 12/03/2022 | AS Saint-Priest | - | Hyères FC | 0:1 | |
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| 22. Round | 19/03/2022 | Lyon-La Duchère | - | AS Saint-Priest | 2:3 | |
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| 23. Round | 26/03/2022 | AS Saint-Priest | - | AS Monaco B | 2:1 | ||||
| 25. Round | 16/04/2022 | AS Saint-Priest | - | GFA Rumilly Vallières | 1:0 | ||||
| 26. Round | 23/04/2022 | AS Saint-Priest | - | SC Toulon | 1:1 | ||||
| 27. Round | 30/04/2022 | Étoile FC | - | AS Saint-Priest | 0:0 | ||||
| 28. Round | 14/05/2022 | AS Saint-Priest | - | GOAL FC | 5:1 |
France
Algeria