| 11. Round | 06/11/2021 | FC Martigues | - | Étoile FC | 0:3 | ||||
| 12. Round | 20/11/2021 | Étoile FC | - | GFA Rumilly Vallières | 1:0 |  |
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| 13. Round | 04/12/2021 | AS Saint-Priest | - | Étoile FC | 1:3 | ||||
| 14. Round | 11/12/2021 | SC Toulon | - | Étoile FC | 0:0 | ||||
| 1. Round | 18/12/2021 | Aubagne FC | - | Étoile FC | 2:1 | ||||
| 16. Round | 22/01/2022 | Jura Sud | - | Étoile FC | 1:0 | ||||
| 15. Round | 29/01/2022 | Étoile FC | - | GOAL FC | 0:0 | ||||
| 17. Round | 05/02/2022 | Étoile FC | - | Olympique Marseille B | 1:1 | ||||
| 19. Round | 19/02/2022 | Étoile FC | - | Olympique Lyonnais B | 2:0 | |
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| 20. Round | 05/03/2022 | RC Grasse | - | Étoile FC | 1:2 | |
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| 21. Round | 12/03/2022 | Étoile FC | - | Louhans-Cuiseaux | 2:1 | ||||
| 22. Round | 19/03/2022 | Hyères FC | - | Étoile FC | 2:1 |  |
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| 23. Round | 26/03/2022 | Étoile FC | - | Lyon-La Duchère | 3:1 | ||||
| 24. Round | 09/04/2022 | AS Monaco B | - | Étoile FC | 0:1 | ||||
| 25. Round | 16/04/2022 | Étoile FC | - | FC Martigues | 1:3 | ||||
| 26. Round | 23/04/2022 | GFA Rumilly Vallières | - | Étoile FC | 2:1 | ||||
| 27. Round | 30/04/2022 | Étoile FC | - | AS Saint-Priest | 0:0 |
France