| 3. Round | 21/08/2021 | Aubagne FC | - | SC Toulon | 1:1 |  |
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| 4. Round | 27/08/2021 | SC Toulon | - | Lyon-La Duchère | 0:2 | ||||
| 5. Round | 04/09/2021 | Jura Sud | - | SC Toulon | 0:0 | ||||
| 6. Round | 11/09/2021 | SC Toulon | - | AS Monaco B | 3:0 | ||||
| 7. Round | 18/09/2021 | Olympique Marseille B | - | SC Toulon | 0:1 | |
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| 9. Round | 09/10/2021 | Marignane Gignac FC | - | SC Toulon | 0:1 | ||||
| 10. Round | 23/10/2021 | SC Toulon | - | GFA Rumilly Vallières | 2:2 | |
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| 12. Round | 20/11/2021 | SC Toulon | - | AS Saint-Priest | 0:1 | ||||
| 13. Round | 04/12/2021 | RC Grasse | - | SC Toulon | 2:1 |  |
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| 16. Round | 16/02/2022 | Hyères FC | - | SC Toulon | 0:0 | ||||
| 19. Round | 19/02/2022 | SC Toulon | - | Jura Sud | 2:1 | |
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| 20. Round | 05/03/2022 | AS Monaco B | - | SC Toulon | 0:1 | |
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| 21. Round | 12/03/2022 | SC Toulon | - | Olympique Marseille B | 4:1 | |
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| 22. Round | 19/03/2022 | FC Martigues | - | SC Toulon | 3:2 | |
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| 25. Round | 16/04/2022 | SC Toulon | - | Olympique Lyonnais B | 2:1 | ||||
| 26. Round | 23/04/2022 | AS Saint-Priest | - | SC Toulon | 1:1 | ||||
| 28. Round | 14/05/2022 | Étoile FC | - | SC Toulon | 2:1 | |
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| 29. Round | 21/05/2022 | Louhans-Cuiseaux | - | SC Toulon | 0:1 |
France