| 13. Round | 04/12/2021 | Hyères FC | - | Marignane Gignac FC | 0:1 | ||||
| 14. Round | 11/12/2021 | Marignane Gignac FC | - | Lyon-La Duchère | 3:0 | ||||
| 15. Round | 15/01/2022 | AS Monaco B | - | Marignane Gignac FC | 0:1 | ||||
| 16. Round | 22/01/2022 | Marignane Gignac FC | - | GFA Rumilly Vallières | 2:0 | ||||
| 17. Round | 05/02/2022 | AS Saint-Priest | - | Marignane Gignac FC | 0:0 | ||||
| 18. Round | 12/02/2022 | Marignane Gignac FC | - | Étoile FC | 1:0 | ||||
| 19. Round | 19/02/2022 | GOAL FC | - | Marignane Gignac FC | 1:0 | ||||
| 20. Round | 05/03/2022 | Marignane Gignac FC | - | Aubagne FC | 0:0 | ||||
| 21. Round | 12/03/2022 | Jura Sud | - | Marignane Gignac FC | 2:0 | ||||
| 22. Round | 19/03/2022 | Marignane Gignac FC | - | Olympique Marseille B | 4:1 |  |
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| 23. Round | 26/03/2022 | SC Toulon | - | Marignane Gignac FC | 1:2 | ||||
| 24. Round | 09/04/2022 | Olympique Lyonnais B | - | Marignane Gignac FC | 3:1 | ||||
| 25. Round | 16/04/2022 | Marignane Gignac FC | - | RC Grasse | 1:2 | ||||
| 26. Round | 23/04/2022 | Louhans-Cuiseaux | - | Marignane Gignac FC | 0:0 |
France
Senegal