| 5. Round | 04/09/2021 | Hyères FC | - | FC Martigues | 0:1 | ||||
| 6. Round | 11/09/2021 | FC Martigues | - | Lyon-La Duchère | 0:3 |  |
|||
| 10. Round | 23/10/2021 | AS Saint-Priest | - | FC Martigues | 1:1 | |
|||
| 11. Round | 06/11/2021 | FC Martigues | - | Étoile FC | 0:3 | ||||
| 12. Round | 20/11/2021 | GOAL FC | - | FC Martigues | 1:1 | ||||
| 13. Round | 04/12/2021 | FC Martigues | - | Aubagne FC | 0:0 | ||||
| 14. Round | 11/12/2021 | Jura Sud | - | FC Martigues | 1:4 | |
|||
| 1. Round | 18/12/2021 | Marignane Gignac FC | - | FC Martigues | 1:1 | ||||
| 19. Round | 19/02/2022 | FC Martigues | - | Hyères FC | 3:1 | ||||
| 18. Round | 26/02/2022 | Louhans-Cuiseaux | - | FC Martigues | 0:2 | ||||
| 22. Round | 19/03/2022 | FC Martigues | - | SC Toulon | 3:2 | |
|||
| 23. Round | 26/03/2022 | GFA Rumilly Vallières | - | FC Martigues | 1:2 | |
|||
| 24. Round | 09/04/2022 | FC Martigues | - | AS Saint-Priest | 1:0 | ||||
| 28. Round | 14/05/2022 | FC Martigues | - | Jura Sud | 3:1 | ||||
| 29. Round | 21/05/2022 | Olympique Marseille B | - | FC Martigues | 1:2 | ||||
| 30. Round | 28/05/2022 | FC Martigues | - | Marignane Gignac FC | 3:0 |
France