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| 1st(1st leg) | Equatorial Guinea | - | Benin | dnp | ||
| 2nd (2nd leg) | Benin | - | Equatorial Guinea | dnp | ||
| 1st(1st leg): 00/00/1980 | 2nd (2nd leg): 00/00/1980 | Winner: Equatorial Guinea | ||||
| 1st(1st leg) | Rwanda | - | Uganda | dnp | ||
| 2nd (2nd leg) | Uganda | - | Rwanda | dnp | ||
| 1st(1st leg): 00/00/1980 | 2nd (2nd leg): 00/00/1980 | Winner: Rwanda | ||||
| 1st(1st leg) | Burkina Faso | - | Gabon | dnp | ||
| 2nd (2nd leg) | Gabon | - | Burkina Faso | dnp | ||
| 1st(1st leg): 00/00/1980 | 2nd (2nd leg): 00/00/1980 | Winner: Burkina Faso | ||||
| 1st(1st leg) | Mozambique | - | Lesotho | 6:1 | ||
| 2nd (2nd leg) | Lesotho | - | Mozambique | 2:1 | ||
| 1st(1st leg): 10/08/1980 | 2nd (2nd leg): 24/08/1980 | Winner: Mozambique | ||||
| 1st(1st leg) | Madagascar | - | Mauritius | 0:0 | ||
| 2nd (2nd leg) | Mauritius | - | Madagascar | 1:1 | ||
| 1st(1st leg): 14/09/1980 | 2nd (2nd leg): 28/09/1980 | Winner: Madagascar | ||||
| 1st(1st leg) | Mali | - | Mauritania | 2:0 | ||
| 2nd (2nd leg) | Mauritania | - | Mali | 2:1 | ||
| 1st(1st leg): 28/09/1980 | 2nd (2nd leg): 12/10/1980 | Winner: Mali | ||||
| 1st(1st leg) | Malawi | - | Zimbabwe | 0:1 | ||
| 2nd (2nd leg) | Zimbabwe | - | Malawi | 1:1 | ||
| 1st(1st leg): 26/10/1980 | 2nd (2nd leg): 09/11/1980 | Winner: Zimbabwe | ||||
| 1st(1st leg) | Liberia | - | Gambia | 0:0 | ||
| 2nd (2nd leg) | Gambia | - | Liberia | 1:1 | ||
| 1st(1st leg): 09/11/1980 | 2nd (2nd leg): 23/11/1980 | Winner: Liberia | ||||
| 1st(1st leg) | Angola | - | Congo | 1:1 | ||
| 2nd (2nd leg) | Congo | - | Angola | 0:0 | ||
| 1st(1st leg): 16/11/1980 | 2nd (2nd leg): 30/11/1980 | Winner: Congo | ||||
| 1st(1st leg) | Senegal | - | Sierra Leone | 2:0 | ||
| 2nd (2nd leg) | Sierra Leone | - | Senegal | 1:2 | ||
| 1st(1st leg): 17/11/1980 | 2nd (2nd leg): 30/11/1980 | Winner: Senegal | ||||
