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| 1st(1st leg) | Emelec | - | UANL Tigres | 1:0 (0:0) | ||
| 2nd (2nd leg) | UANL Tigres | - | Emelec | 2:0 (1:0) | ||
| 1st(1st leg): 20/05/2015 02:00 | 2nd (2nd leg): 27/05/2015 02:00 | Winner: UANL Tigres | ||||
| 1st(1st leg) | Santa Fe | - | Internacional | 1:0 (0:0) | ||
| 2nd (2nd leg) | Internacional | - | Santa Fe | 2:0 (1:0) | ||
| 1st(1st leg): 21/05/2015 02:00 | 2nd (2nd leg): 27/05/2015 23:30 | Winner: Internacional | ||||
| 1st(1st leg) | Guaraní | - | Racing Club | 1:0 (0:0) | ||
| 2nd (2nd leg) | Racing Club | - | Guaraní | 0:0 (0:0) | ||
| 1st(1st leg): 21/05/2015 23:45 | 2nd (2nd leg): 29/05/2015 01:00 | Winner: Guaraní | ||||
| 1st(1st leg) | River Plate | - | Cruzeiro | 0:1 (0:0) | ||
| 2nd (2nd leg) | Cruzeiro | - | River Plate | 0:3 (0:2) | ||
| 1st(1st leg): 22/05/2015 02:00 | 2nd (2nd leg): 28/05/2015 02:00 | Winner: River Plate | ||||
