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| 1st(1st leg) | Arsenal de Sarandí | - | River Plate | 2:1 (0:1) | ||
| 2nd (2nd leg) | River Plate | - | Arsenal de Sarandí | 0:0 (0:0) | ||
| 1st(1st leg): 07/09/2004 | 2nd (2nd leg): 30/09/2004 | Winner: Arsenal de Sarandí | ||||
| 1st(1st leg) | San Lorenzo | - | Boca Juniors | 1:0 (0:0) | ||
| 2nd (2nd leg) | Boca Juniors | - | San Lorenzo | 4:1 (1:1, 2:1) aet | ||
| 1st(1st leg): 16/09/2004 | 2nd (2nd leg): 29/09/2004 | Winner: Boca Juniors | ||||
| 1st(1st leg) | LDU Quito | - | Cienciano | 4:0 (4:0) | ||
| 2nd (2nd leg) | Cienciano | - | LDU Quito | 2:2 (2:1) | ||
| 1st(1st leg): 28/09/2004 | 2nd (2nd leg): 05/10/2004 | Winner: LDU Quito | ||||
| 1st(1st leg) | Universidad de Concepción | - | Bolívar | 0:0 (0:0) | ||
| 2nd (2nd leg) | Bolívar | - | Universidad de Concepción | 4:2 (4:1) | ||
| 1st(1st leg): 28/09/2004 | 2nd (2nd leg): 19/10/2004 | Winner: Bolívar | ||||
| 1st(1st leg) | Alianza Atlético | - | Atlético Junior | 0:2 (0:1) | ||
| 2nd (2nd leg) | Atlético Junior | - | Alianza Atlético | 4:1 (2:0) | ||
| 1st(1st leg): 30/09/2004 | 2nd (2nd leg): 19/10/2004 | Winner: Atlético Junior | ||||
| 1st(1st leg) | Peñarol | - | Cerro Porteño | 1:3 (0:2) | ||
| 2nd (2nd leg) | Cerro Porteño | - | Peñarol | 1:2 (0:0) | ||
| 1st(1st leg): 06/10/2004 | 2nd (2nd leg): 21/10/2004 | Winner: Cerro Porteño | ||||
| 1st(1st leg) | Santos FC | - | São Paulo FC | 1:0 (0:0) | ||
| 2nd (2nd leg) | São Paulo FC | - | Santos FC | 1:1 (1:0) | ||
| 1st(1st leg): 10/10/2004 | 2nd (2nd leg): 20/10/2004 | Winner: Santos FC | ||||
| 1st(1st leg) | Internacional | - | Cruzeiro | 3:1 (1:1) | ||
| 2nd (2nd leg) | Cruzeiro | - | Internacional | 0:1 (0:0) | ||
| 1st(1st leg): 10/10/2004 | 2nd (2nd leg): 20/10/2004 | Winner: Internacional | ||||
