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| 1st(1st leg) | Castilla CF | - | Athletic Bilbao | 2:1 | ||
| 2nd (2nd leg) | Athletic Bilbao | - | Castilla CF | 6:7 pso | ||
| 1st(1st leg): 15/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: Castilla CF | ||||
| 1st(1st leg) | Espanyol Barcelona | - | FC Barcelona | 1:3 | ||
| 2nd (2nd leg) | FC Barcelona | - | Espanyol Barcelona | 1:0 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: FC Barcelona | ||||
| 1st(1st leg) | CA Osasuna | - | RC Celta | 2:0 | ||
| 2nd (2nd leg) | RC Celta | - | CA Osasuna | 0:1 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: CA Osasuna | ||||
| 1st(1st leg) | Atlético Madrid | - | UD Las Palmas | 0:0 | ||
| 2nd (2nd leg) | UD Las Palmas | - | Atlético Madrid | 1:3 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: Atlético Madrid | ||||
| 1st(1st leg) | Sporting Gijón | - | Real Sociedad | 0:0 | ||
| 2nd (2nd leg) | Real Sociedad | - | Sporting Gijón | 4:0 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: Real Sociedad | ||||
| 1st(1st leg) | Cádiz CF | - | Real Madrid | 1:1 | ||
| 2nd (2nd leg) | Real Madrid | - | Cádiz CF | 4:2 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: Real Madrid | ||||
| 1st(1st leg) | CE Sabadell | - | Real Betis | 0:0 | ||
| 2nd (2nd leg) | Real Betis | - | CE Sabadell | 0:1 | ||
| 1st(1st leg): 16/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: CE Sabadell | ||||
| 1st(1st leg) | Sevilla FC | - | CD Castellón | 1:1 | ||
| 2nd (2nd leg) | CD Castellón | - | Sevilla FC | 2:1 | ||
| 1st(1st leg): 30/12/1987 | 2nd (2nd leg): 06/01/1988 | Winner: CD Castellón | ||||
