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| 1st(1st leg) | RCD Mallorca | - | Getafe CF | 1:2 (0:0) | ||
| 2nd (2nd leg) | Getafe CF | - | RCD Mallorca | 0:1 (0:1) | ||
| 1st(1st leg): 20/01/2010 19:00 | 2nd (2nd leg): 28/01/2010 19:00 | Winner: Getafe CF | ||||
| 1st(1st leg) | Deportivo La Coruña | - | Sevilla FC | 0:3 (0:1) | ||
| 2nd (2nd leg) | Sevilla FC | - | Deportivo La Coruña | 0:1 (0:1) | ||
| 1st(1st leg): 20/01/2010 21:00 | 2nd (2nd leg): 27/01/2010 21:00 | Winner: Sevilla FC | ||||
| 1st(1st leg) | Racing Santander | - | CA Osasuna | 2:1 (0:0) | ||
| 2nd (2nd leg) | CA Osasuna | - | Racing Santander | 0:3 (0:2) | ||
| 1st(1st leg): 21/01/2010 19:00 | 2nd (2nd leg): 27/01/2010 19:00 | Winner: Racing Santander | ||||
| 1st(1st leg) | Atlético Madrid | - | RC Celta | 1:1 (1:1) | ||
| 2nd (2nd leg) | RC Celta | - | Atlético Madrid | 0:1 (0:1) | ||
| 1st(1st leg): 21/01/2010 21:00 | 2nd (2nd leg): 28/01/2010 21:00 | Winner: Atlético Madrid | ||||
