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| 20/01/2023 | 20:10 | Olympique Marseille | - | Stade Rennes | 1:0 (0:0) | |
| 21/01/2023 | 14:30 | Chambéry SF | - | Olympique Lyon | 0:3 (0:2) | |
| 17:00 | Stade Plabennec | - | Grenoble Foot 38 | 0:1 (0:1) | ||
| 17:00 | FC Chamalières | - | Paris FC | 0:4 (0:2) | ||
| 17:00 | SC Bastia | - | FC Lorient | 1:4 (0:0, 1:1) pso | ||
| 17:00 | Vendée Les Herbiers | - | Stade Reims | 0:3 (0:1) | ||
| 17:00 | Toulouse FC | - | AC Ajaccio | 2:0 (0:0) | ||
| 17:00 | RC Grasse | - | Rodez AF | 4:5 (0:0, 0:0) pso | ||
| 19:45 | Strasbourg Koenigshoffen | - | Angers SCO | 0:1 (0:1) | ||
| 22/01/2023 | 17:30 | Chamois Niortais | - | AJ Auxerre | 0:4 (0:2) | |
| 17:30 | Lille OSC | - | Pau FC | 2:0 (1:0) | ||
| 17:30 | ES Thaon | - | FC Nantes | 2:4 (0:0, 0:0) pso | ||
| 17:30 | Le Puy Foot 43 | - | Vierzon FC | 3:5 (0:0, 0:0) pso | ||
| 17:30 | ASM Belfort | - | FC Annecy | 3:4 (1:0, 1:1) pso | ||
| 20:00 | Stade Brest | - | RC Lens | 1:3 (1:3) | ||
| 23/01/2023 | 19:45 | Pays de Cassel | - | Paris Saint-Germain | 0:7 (0:4) |
