Copa Libertadores   M. W D L goals
  at home 3 2 0 1 5 : 2
  Away 3 1 0 2 5 : 7
  6 3 0 3 10 : 9
Copa Sudamericana   M. W D L goals
  at home 1 0 0 1 1 : 2
  Away 1 0 0 1 2 : 3
  2 0 0 2 3 : 5
Copa Conmebol   M. W D L goals
  at home 1 1 0 0 3 : 0
  Away 1 0 1 0 2 : 2
  2 1 1 0 5 : 2
overall   M. W D L goals
  at home 5 3 0 2 9 : 4
  Away 5 1 1 3 9 : 12
  Neutral Place 0 0 0 0 0 : 0
  10 4 1 5 18 : 16
Copa Libertadores
2020 Round of 16 Santos FC - LDU Quito 0:1 (0:0)
2020 Round of 16 LDU Quito - Santos FC 1:2 (1:1)
2005 Group 2 Santos FC - LDU Quito 3:1 (1:1)
2005 Group 2 LDU Quito - Santos FC 2:1 (2:1)
2004 Round of 16 Santos FC - LDU Quito 5:3 (1:0, 2:0, 2:0) pso
2004 Round of 16 LDU Quito - Santos FC 4:2 (1:2)
Copa Sudamericana
2004 Quarter-finals Santos FC - LDU Quito 1:2 (0:1)
2004 Quarter-finals LDU Quito - Santos FC 3:2 (2:1)
Copa Conmebol
1998 Quarter-finals Santos FC - LDU Quito 3:0
1998 Quarter-finals LDU Quito - Santos FC 2:2

For games that were decided on penalties the score after 120 minutes will be included in the ranking