| 1. Round | 08/07/2012 | Deportes Iquique | - | Colo-Colo | 0:1 | ||||
| 2. Round | 14/07/2012 | Deportes Iquique | - | Antofagasta | 2:1 |  |
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| 3. Round | 21/07/2012 | Deportes Iquique | - | Universidad de Chile | 0:0 | ||||
| 4. Round | 28/07/2012 | Rangers | - | Deportes Iquique | 5:0 | ||||
| 5. Round | 05/08/2012 | Huachipato | - | Deportes Iquique | 4:1 | ||||
| 7. Round | 19/08/2012 | Deportes Iquique | - | Cobresal | 3:2 | ||||
| 8. Round | 25/08/2012 | O'Higgins | - | Deportes Iquique | 0:1 | ||||
| 9. Round | 01/09/2012 | Deportes Iquique | - | Universidad Católica | 3:2 | ||||
| 11. Round | 22/09/2012 | La Serena | - | Deportes Iquique | 2:3 | ||||
| 12. Round | 30/09/2012 | Deportes Iquique | - | Cobreloa | 1:1 | ||||
| 13. Round | 07/10/2012 | Unión La Calera | - | Deportes Iquique | 1:1 | ||||
| 15. Round | 25/10/2012 | Santiago Wanderers | - | Deportes Iquique | 2:1 | ||||
| 16. Round | 03/11/2012 | Deportes Iquique | - | Unión Española | 2:4 | ||||
| 17. Round | 14/11/2012 | Unión San Felipe | - | Deportes Iquique | 1:2 |
Argentina