| 1. Round | 17/01/2016 | Universidad Católica | - | Deportes Iquique | 2:2 | ||||
| 2. Round | 23/01/2016 | Deportes Iquique | - | Huachipato | 1:1 | ||||
| 3. Round | 31/01/2016 | O'Higgins | - | Deportes Iquique | 0:0 |  |
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| 4. Round | 07/02/2016 | Deportes Iquique | - | Colo-Colo | 0:0 | ||||
| 5. Round | 14/02/2016 | San Luis | - | Deportes Iquique | 3:1 | |
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| 8. Round | 06/03/2016 | Deportes Iquique | - | Audax Italiano | 1:1 | ||||
| 9. Round | 12/03/2016 | Deportes Iquique | - | Santiago Wanderers | 1:2 | ||||
| 10. Round | 19/03/2016 | Antofagasta | - | Deportes Iquique | 2:3 | |
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| 11. Round | 02/04/2016 | Deportes Iquique | - | Universidad de Concepción | 3:1 | ||||
| 12. Round | 09/04/2016 | Universidad de Chile | - | Deportes Iquique | 2:1 | |
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| 13. Round | 17/04/2016 | San Marcos | - | Deportes Iquique | 0:1 | ||||
| 14. Round | 23/04/2016 | Deportes Iquique | - | Unión Española | 2:3 | ||||
| 15. Round | 29/04/2016 | Unión La Calera | - | Deportes Iquique | 2:4 |
Argentina