 |
 |
|
|
| 19/10/2021 | 22:30 | Audax Italiano | - | Ñublense | 0:3 (0:1) | |
| 20/10/2021 | 01:00 | O'Higgins | - | Melipilla | 1:2 (1:1) | |
| 18:00 | La Serena | - | Colo-Colo | 1:4 (0:2) | ||
| 22:30 | Universidad Católica | - | Santiago Wanderers | 3:2 (3:1) | ||
| 21/10/2021 | 01:00 | Everton | - | Huachipato | 1:0 (1:0) | |
| 20:00 | Antofagasta | - | Unión Española | 1:2 (1:0) | ||
| 22:30 | Universidad de Chile | - | Palestino | 0:1 (0:0) | ||
| 22/10/2021 | 01:00 | Unión La Calera | - | Cobresal | 1:2 (1:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colo-Colo | 25 | 16 | 4 | 5 | 43:21 | 22 | 52 |
| 2 |
|
Universidad Católica | 25 | 16 | 2 | 7 | 49:31 | 18 | 50 |
| 3 |
|
Audax Italiano | 26 | 12 | 8 | 6 | 32:27 | 5 | 44 |
| 4 |
|
Unión La Calera | 25 | 13 | 5 | 7 | 31:27 | 4 | 44 |
| 5 |
|
Unión Española | 26 | 13 | 3 | 10 | 42:37 | 5 | 42 |
| 6 |
|
Everton | 25 | 10 | 7 | 8 | 22:21 | 1 | 37 |
| 7 |
|
Cobresal | 26 | 10 | 5 | 11 | 33:30 | 3 | 35 |
| 8 |
|
Antofagasta | 25 | 9 | 8 | 8 | 30:31 | -1 | 35 |
| 9 |
|
Universidad de Chile | 25 | 9 | 7 | 9 | 30:28 | 2 | 34 |
| 10 |
|
Ñublense | 26 | 8 | 9 | 9 | 35:31 | 4 | 33 |
| 11 |
|
Palestino | 25 | 9 | 5 | 11 | 36:37 | -1 | 32 |
| 12 |
|
La Serena | 26 | 8 | 8 | 10 | 33:34 | -1 | 32 |
| 13 |
|
O'Higgins | 26 | 7 | 8 | 11 | 24:35 | -11 | 29 |
| 14 |
|
Curicó Unido | 25 | 6 | 9 | 10 | 29:33 | -4 | 27 |
| 15 |
|
Melipilla | 26 | 6 | 8 | 12 | 29:44 | -15 | 26 |
| 16 |
|
Huachipato | 25 | 4 | 11 | 10 | 26:36 | -10 | 23 |
| 17 |
|
Santiago Wanderers | 25 | 5 | 3 | 17 | 21:42 | -21 | 18 |
| Copa Libertadores | |
| Qualification | |
| Copa Sudamericana | |
| Playoffs | |
| Relegation |
