| 37. Round | 12/03/2011 | Leyton Orient | - | Oldham Athletic | 1:0 | ||||
| 23. Round | 15/03/2011 | Hartlepool United | - | Leyton Orient | 0:1 | ||||
| 38. Round | 19/03/2011 | Brentford FC | - | Leyton Orient | 2:1 | ||||
| 33. Round | 22/03/2011 | Leyton Orient | - | Dagenham & Redbridge | 1:1 | ||||
| 39. Round | 26/03/2011 | Leyton Orient | - | Yeovil Town | 1:5 | ||||
| 40. Round | 02/04/2011 | Charlton Athletic | - | Leyton Orient | 3:1 | ||||
| 21. Round | 05/04/2011 | Leyton Orient | - | Plymouth Argyle | 2:0 | ||||
| 41. Round | 09/04/2011 | Leyton Orient | - | Southampton FC | 0:2 | ||||
| 19. Round | 12/04/2011 | Leyton Orient | - | Carlisle United | 0:0 | ||||
| 42. Round | 16/04/2011 | Exeter City | - | Leyton Orient | 2:1 | ||||
| 43. Round | 22/04/2011 | Leyton Orient | - | Peterborough United | 2:1 |  |
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| 44. Round | 25/04/2011 | Carlisle United | - | Leyton Orient | 0:1 | ||||
| 45. Round | 30/04/2011 | Leyton Orient | - | Tranmere Rovers | 0:3 | ||||
| 46. Round | 07/05/2011 | Plymouth Argyle | - | Leyton Orient | 1:4 | |
England