| 6. Round | 11/09/2010 | Brighton & Hove Albion | - | Milton Keynes Dons | 2:0 | ||||
| 8. Round | 25/09/2010 | Peterborough United | - | Milton Keynes Dons | 2:1 | ||||
| 10. Round | 02/10/2010 | Milton Keynes Dons | - | Colchester United | 1:1 |  |
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| 15. Round | 02/11/2010 | Milton Keynes Dons | - | Yeovil Town | 3:2 | ||||
| 24. Round | 01/01/2011 | Milton Keynes Dons | - | Bristol Rovers | 2:0 | ||||
| 26. Round | 08/01/2011 | Exeter City | - | Milton Keynes Dons | 1:1 | ||||
| 27. Round | 15/01/2011 | Milton Keynes Dons | - | Tranmere Rovers | 2:0 | ||||
| 19. Round | 18/01/2011 | Milton Keynes Dons | - | Plymouth Argyle | 1:3 | ||||
| 28. Round | 22/01/2011 | Dagenham & Redbridge | - | Milton Keynes Dons | 0:1 | ||||
| 22. Round | 25/01/2011 | Leyton Orient | - | Milton Keynes Dons | 2:2 | ||||
| 31. Round | 05/02/2011 | Sheffield Wednesday | - | Milton Keynes Dons | 2:2 | ||||
| 32. Round | 12/02/2011 | Milton Keynes Dons | - | Brentford FC | 1:1 | ||||
| 36. Round | 08/03/2011 | Milton Keynes Dons | - | Charlton Athletic | 2:0 | ||||
| 46. Round | 07/05/2011 | Oldham Athletic | - | Milton Keynes Dons | 1:2 |
England
