| 1. Round | 13/09/2020 | Ipswich Town | - | Wigan Athletic | 2:0 | ||||
| 8. Round | 24/10/2020 | Wigan Athletic | - | Plymouth Argyle | 1:1 | ||||
| 9. Round | 27/10/2020 | Milton Keynes Dons | - | Wigan Athletic | 2:0 | ||||
| 10. Round | 31/10/2020 | Wigan Athletic | - | Northampton Town | 2:3 | ||||
| 11. Round | 03/11/2020 | Blackpool FC | - | Wigan Athletic | 1:0 | ||||
| 14. Round | 24/11/2020 | Wigan Athletic | - | Bristol Rovers | 0:0 | ||||
| 15. Round | 01/12/2020 | Lincoln City | - | Wigan Athletic | 2:1 | ||||
| 16. Round | 05/12/2020 | Sunderland AFC | - | Wigan Athletic | 0:1 | ||||
| 17. Round | 12/12/2020 | Wigan Athletic | - | Accrington Stanley | 4:3 | ||||
| 18. Round | 15/12/2020 | Wigan Athletic | - | Rochdale AFC | 0:5 |  |
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| 20. Round | 26/12/2020 | Wigan Athletic | - | Shrewsbury Town | 1:1 | ||||
| 21. Round | 29/12/2020 | Burton Albion | - | Wigan Athletic | 3:4 | ||||
| 24. Round | 16/01/2021 | Rochdale AFC | - | Wigan Athletic | 3:3 |
England