| 4. Round | 01/09/2012 | Plymouth Argyle | - | Northampton Town | 3:2 |  |
|||
| 5. Round | 08/09/2012 | Torquay United | - | Plymouth Argyle | 0:0 | ||||
| 6. Round | 15/09/2012 | Plymouth Argyle | - | Port Vale FC | 1:3 | ||||
| 7. Round | 18/09/2012 | Plymouth Argyle | - | Bristol Rovers | 1:1 | ||||
| 8. Round | 22/09/2012 | Morecambe FC | - | Plymouth Argyle | 2:3 | ||||
| 9. Round | 29/09/2012 | Plymouth Argyle | - | Southend United | 1:1 |  |
|||
| 10. Round | 02/10/2012 | Wycombe Wanderers | - | Plymouth Argyle | 1:1 | ||||
| 11. Round | 06/10/2012 | Plymouth Argyle | - | AFC Wimbledon | 1:2 | ||||
| 12. Round | 13/10/2012 | Barnet FC | - | Plymouth Argyle | 1:4 | |
|||
| 13. Round | 20/10/2012 | Plymouth Argyle | - | Rochdale AFC | 3:1 | |
|||
| 14. Round | 23/10/2012 | Cheltenham Town | - | Plymouth Argyle | 2:1 | ||||
| 15. Round | 27/10/2012 | Rotherham United | - | Plymouth Argyle | 1:0 | |
|||
| 16. Round | 07/11/2012 | Plymouth Argyle | - | Burton Albion | 1:2 | ||||
| 18. Round | 17/11/2012 | Fleetwood Town | - | Plymouth Argyle | 3:0 | ||||
| 19. Round | 20/11/2012 | Bradford City | - | Plymouth Argyle | 1:0 | ||||
| 20. Round | 24/11/2012 | Plymouth Argyle | - | Chesterfield FC | 0:1 |
England