| 28. Round | 14/01/2006 | Grimsby Town | - | Mansfield Town | 2:1 | ||||
| 22. Round | 17/01/2006 | Darlington FC | - | Grimsby Town | 0:0 |  |
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| 29. Round | 21/01/2006 | Torquay United | - | Grimsby Town | 2:2 |  |
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| 27. Round | 24/01/2006 | Stockport County | - | Grimsby Town | 2:1 | |
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| 31. Round | 04/02/2006 | Notts County | - | Grimsby Town | 0:1 | ||||
| 33. Round | 14/02/2006 | Mansfield Town | - | Grimsby Town | 2:1 | ||||
| 35. Round | 25/02/2006 | Grimsby Town | - | Chester City | 1:0 | ||||
| 36. Round | 04/03/2006 | Rushden & Diamonds FC | - | Grimsby Town | 1:1 | |
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| 37. Round | 11/03/2006 | Grimsby Town | - | Barnet FC | 3:0 | ||||
| 38. Round | 18/03/2006 | Grimsby Town | - | Bury FC | 2:1 | ||||
| 34. Round | 21/03/2006 | Rochdale AFC | - | Grimsby Town | 2:2 | |
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| 39. Round | 25/03/2006 | Lincoln City | - | Grimsby Town | 5:0 | ||||
| 41. Round | 08/04/2006 | Carlisle United | - | Grimsby Town | 1:0 | ||||
| 42. Round | 15/04/2006 | Grimsby Town | - | Shrewsbury Town | 1:1 | ||||
| 45. Round | 29/04/2006 | Macclesfield Town | - | Grimsby Town | 1:1 |
England