| 1. Round | 29/08/2022 | Akritas Chlorakas | - | Omonia Nikosia | 1:0 | ||||
| 4. Round | 18/09/2022 | Omonia Nikosia | - | Enosis Neon Paralimni | 4:0 | ||||
| 5. Round | 01/10/2022 | Doxa Katokopias | - | Omonia Nikosia | 0:2 | ||||
| 6. Round | 10/10/2022 | AEL Limassol | - | Omonia Nikosia | 1:0 | ||||
| 7. Round | 18/10/2022 | Omonia Nikosia | - | Nea Salamina | 0:1 | ||||
| 10. Round | 07/11/2022 | Aris Limassol | - | Omonia Nikosia | 1:1 | ||||
| 11. Round | 11/11/2022 | Omonia Nikosia | - | Olympiakos Nikosia | 4:0 |  |
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| 14. Round | 11/12/2022 | Omonia Nikosia | - | Akritas Chlorakas | 1:0 | ||||
| 15. Round | 16/12/2022 | AEK Larnaca | - | Omonia Nikosia | 2:1 | ||||
| 16. Round | 22/12/2022 | Omonia Nikosia | - | Apollon Limassol | 2:0 | ||||
| 17. Round | 02/01/2023 | Enosis Neon Paralimni | - | Omonia Nikosia | 0:3 | ||||
| 18. Round | 07/01/2023 | Omonia Nikosia | - | Doxa Katokopias | 2:0 |  |
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| 19. Round | 16/01/2023 | Omonia Nikosia | - | AEL Limassol | 1:0 | ||||
| 20. Round | 22/01/2023 | Nea Salamina | - | Omonia Nikosia | 2:1 | ||||
| 22. Round | 02/02/2023 | Anorthosis Famagusta | - | Omonia Nikosia | 4:1 | ||||
| 23. Round | 10/02/2023 | Omonia Nikosia | - | Aris Limassol | 1:2 | ||||
| 25. Round | 25/02/2023 | Omonia Nikosia | - | APOEL Nikosia | 0:2 |
England