| 1. Round | 04/09/2021 | Aston Villa WFC [Women] | - | Leicester City WFC [Women] | 2:1 | ||||
| 2. Round | 12/09/2021 | Leicester City WFC [Women] | - | Manchester United WFC [Women] | 1:3 | ||||
| 4. Round | 03/10/2021 | Leicester City WFC [Women] | - | Tottenham Hotspur WFC [Women] | 0:2 | ||||
| 6. Round | 07/11/2021 | Leicester City WFC [Women] | - | Manchester City WFC [Women] | 1:4 | ||||
| 10. Round | 19/12/2021 | Leicester City WFC [Women] | - | Birmingham City WFC [Women] | 2:0 | ||||
| 15. Round | 13/02/2022 | Leicester City WFC [Women] | - | West Ham United WFC [Women] | 3:0 |  |
England