| 2. Round | 14/08/2022 | Blackburn Rovers U21 | - | Wolverhampton Wanderers U21 | 0:1 | ||||
| 3. Round | 22/08/2022 | Wolverhampton Wanderers U21 | - | Brighton & Hove Albion U21 | 2:0 | ||||
| 5. Round | 05/09/2022 | Wolverhampton Wanderers U21 | - | Fulham FC U21 | 1:1 |  |
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| 8. Round | 02/10/2022 | Wolverhampton Wanderers U21 | - | Manchester City U21 | 1:3 | ||||
| 12. Round | 31/10/2022 | Wolverhampton Wanderers U21 | - | Leicester City U21 | 3:0 |
England