| 5. Round | 11/09/2010 | Cardiff City | - | Hull City | 2:0 | ||||
| 6. Round | 14/09/2010 | Hull City | - | Derby County | 2:0 |  |
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| 7. Round | 18/09/2010 | Hull City | - | Nottingham Forest | 0:0 | ||||
| 8. Round | 25/09/2010 | Norwich City | - | Hull City | 0:2 |  |
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| 9. Round | 28/09/2010 | Burnley FC | - | Hull City | 4:0 | ||||
| 10. Round | 02/10/2010 | Hull City | - | Coventry City | 0:0 | |
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| 11. Round | 16/10/2010 | Leicester City | - | Hull City | 1:1 | |
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| 12. Round | 19/10/2010 | Hull City | - | Sheffield United | 0:1 | |
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| 13. Round | 23/10/2010 | Hull City | - | Portsmouth FC | 1:2 | |
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| 15. Round | 06/11/2010 | Hull City | - | Scunthorpe United | 0:1 | ||||
| 16. Round | 09/11/2010 | Leeds United | - | Hull City | 2:2 | |
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| 17. Round | 12/11/2010 | Preston North End | - | Hull City | 0:2 |
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