| 14. Round | 01/12/2018 | Southampton FC | - | Manchester United | 2:2 | ||||
| 15. Round | 05/12/2018 | Manchester United | - | Arsenal FC | 2:2 | ||||
| 16. Round | 08/12/2018 | Manchester United | - | Fulham FC | 4:1 |  |
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| 17. Round | 16/12/2018 | Liverpool FC | - | Manchester United | 3:1 | |
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| 19. Round | 26/12/2018 | Manchester United | - | Huddersfield Town | 3:1 | ||||
| 22. Round | 13/01/2019 | Tottenham Hotspur | - | Manchester United | 0:1 | ||||
| 23. Round | 19/01/2019 | Manchester United | - | Brighton & Hove Albion | 2:1 | ||||
| 26. Round | 09/02/2019 | Fulham FC | - | Manchester United | 0:3 | ||||
| 28. Round | 27/02/2019 | Crystal Palace | - | Manchester United | 1:3 | ||||
| 29. Round | 02/03/2019 | Manchester United | - | Southampton FC | 3:2 | ||||
| 30. Round | 10/03/2019 | Arsenal FC | - | Manchester United | 2:0 | ||||
| 33. Round | 02/04/2019 | Wolverhampton Wanderers | - | Manchester United | 2:1 | |
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| 34. Round | 13/04/2019 | Manchester United | - | West Ham United | 2:1 | ||||
| 35. Round | 21/04/2019 | Everton FC | - | Manchester United | 4:0 | ||||
| 37. Round | 05/05/2019 | Huddersfield Town | - | Manchester United | 1:1 | ||||
| 38. Round | 12/05/2019 | Manchester United | - | Cardiff City | 0:2 |
Portugal
