| 1. Round | 04/09/2021 | Aston Villa WFC [Women] | - | Leicester City WFC [Women] | 2:1 | ||||
| 2. Round | 11/09/2021 | West Ham United WFC [Women] | - | Aston Villa WFC [Women] | 1:1 | ||||
| 4. Round | 02/10/2021 | Aston Villa WFC [Women] | - | Arsenal WFC [Women] | 0:4 | ||||
| 6. Round | 06/11/2021 | Aston Villa WFC [Women] | - | Chelsea FC Women [Women] | 0:1 | ||||
| 7. Round | 14/11/2021 | Birmingham City WFC [Women] | - | Aston Villa WFC [Women] | 0:1 | ||||
| 8. Round | 20/11/2021 | Manchester City WFC [Women] | - | Aston Villa WFC [Women] | 5:0 | ||||
| 10. Round | 19/12/2021 | Manchester United WFC [Women] | - | Aston Villa WFC [Women] | 5:0 |
England