| 15. Round | 11/02/2023 | Aston Villa [U18] | - | Southampton FC [U18] | 2:4 | ||||
| 17. Round | 25/02/2023 | West Bromwich Albion [U18] | - | Southampton FC [U18] | 0:1 | ||||
| 12. Round | 04/03/2023 | Fulham FC [U18] | - | Southampton FC [U18] | 5:2 | ||||
| 13. Round | 11/03/2023 | Southampton FC [U18] | - | Leicester City [U18] | 0:2 | ||||
| 18. Round | 18/03/2023 | Chelsea FC [U18] | - | Southampton FC [U18] | 5:2 | ||||
| 19. Round | 01/04/2023 | Southampton FC [U18] | - | Crystal Palace [U18] | 1:7 | ||||
| 11. Round | 12/04/2023 | Tottenham Hotspur [U18] | - | Southampton FC [U18] | 4:2 | ||||
| 20. Round | 15/04/2023 | Brighton & Hove Albion [U18] | - | Southampton FC [U18] | 0:2 | ||||
| 10. Round | 26/04/2023 | Southampton FC [U18] | - | West Bromwich Albion [U18] | 3:4 | ||||
| 22. Round | 29/04/2023 | Norwich City [U18] | - | Southampton FC [U18] | 4:1 |
Wales