| 23. Round | 15/01/1921 | Preston North End | - | Derby County | 2:1 | ||||
| 26. Round | 05/02/1921 | Sheffield United | - | Preston North End | 1:0 | ||||
| 25. Round | 07/02/1921 | Preston North End | - | Sheffield United | 2:0 | ||||
| 27. Round | 12/02/1921 | Preston North End | - | Bolton Wanderers | 1:2 | ||||
| 29. Round | 26/02/1921 | Preston North End | - | Arsenal FC | 0:1 | ||||
| 31. Round | 12/03/1921 | Preston North End | - | Manchester City | 0:1 | ||||
| 28. Round | 04/04/1921 | Bolton Wanderers | - | Preston North End | 3:0 | ||||
| 42. Round | 07/05/1921 | Preston North End | - | Bradford City | 1:1 |
England