| 1. Round | 07/08/2010 | Reading FC | - | Scunthorpe United | 1:2 |  |
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| 2. Round | 14/08/2010 | Scunthorpe United | - | Norwich City | 0:1 | ||||
| 11. Round | 16/10/2010 | Scunthorpe United | - | Doncaster Rovers | 1:3 | ||||
| 12. Round | 19/10/2010 | Preston North End | - | Scunthorpe United | 2:3 | ||||
| 13. Round | 23/10/2010 | Watford FC | - | Scunthorpe United | 0:2 | ||||
| 14. Round | 30/10/2010 | Scunthorpe United | - | Leeds United | 1:4 | ||||
| 18. Round | 20/11/2010 | Derby County | - | Scunthorpe United | 3:2 | ||||
| 19. Round | 27/11/2010 | Scunthorpe United | - | Coventry City | 0:2 | ||||
| 20. Round | 04/12/2010 | Millwall FC | - | Scunthorpe United | 3:0 | ||||
| 24. Round | 28/12/2010 | Burnley FC | - | Scunthorpe United | 0:2 | ||||
| 25. Round | 01/01/2011 | Doncaster Rovers | - | Scunthorpe United | 3:0 | ||||
| 26. Round | 03/01/2011 | Scunthorpe United | - | Watford FC | 1:2 |
England