| 1. Round | 06/08/2021 | AFC Bournemouth | - | West Bromwich Albion | 2:2 | ||||
| 2. Round | 14/08/2021 | Nottingham Forest | - | AFC Bournemouth | 1:2 | ||||
| 3. Round | 18/08/2021 | Birmingham City | - | AFC Bournemouth | 0:2 | ||||
| 4. Round | 21/08/2021 | AFC Bournemouth | - | Blackpool FC | 2:2 | ||||
| 12. Round | 16/10/2021 | Bristol City | - | AFC Bournemouth | 0:2 | ||||
| 13. Round | 19/10/2021 | Stoke City | - | AFC Bournemouth | 0:1 |  |
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| 14. Round | 23/10/2021 | AFC Bournemouth | - | Huddersfield Town | 3:0 | |
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| 15. Round | 30/10/2021 | Reading FC | - | AFC Bournemouth | 0:2 | |
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| 17. Round | 06/11/2021 | AFC Bournemouth | - | Swansea City | 4:0 | ||||
| 18. Round | 21/11/2021 | Derby County | - | AFC Bournemouth | 3:2 | ||||
| 19. Round | 24/11/2021 | Millwall FC | - | AFC Bournemouth | 1:1 | |
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| 20. Round | 27/11/2021 | AFC Bournemouth | - | Coventry City | 2:2 | ||||
| 23. Round | 18/12/2021 | Middlesbrough FC | - | AFC Bournemouth | 1:0 | ||||
| 46. Round | 07/05/2022 | AFC Bournemouth | - | Millwall FC | 1:0 |
Ireland