| 3. Round | 26/09/2020 | Northampton Town | - | Hull City | 0:2 | ||||
| 4. Round | 03/10/2020 | Bristol Rovers | - | Northampton Town | 2:0 | ||||
| 5. Round | 10/10/2020 | Northampton Town | - | Peterborough United | 0:2 | ||||
| 7. Round | 20/10/2020 | Northampton Town | - | Swindon Town | 2:1 |  |
|||
| 9. Round | 27/10/2020 | Portsmouth FC | - | Northampton Town | 4:0 | ||||
| 10. Round | 31/10/2020 | Wigan Athletic | - | Northampton Town | 2:3 | ||||
| 11. Round | 03/11/2020 | Northampton Town | - | Milton Keynes Dons | 0:0 | ||||
| 12. Round | 14/11/2020 | Northampton Town | - | Accrington Stanley | 0:1 | ||||
| 13. Round | 21/11/2020 | Burton Albion | - | Northampton Town | 1:3 |  |
|||
| 14. Round | 24/11/2020 | Rochdale AFC | - | Northampton Town | 1:1 | |
|||
| 15. Round | 01/12/2020 | Northampton Town | - | Fleetwood Town | 1:0 | ||||
| 16. Round | 05/12/2020 | Northampton Town | - | Doncaster Rovers | 0:2 | ||||
| 17. Round | 12/12/2020 | Crewe Alexandra | - | Northampton Town | 2:1 | ||||
| 18. Round | 15/12/2020 | Oxford United | - | Northampton Town | 4:0 | ||||
| 19. Round | 19/12/2020 | Northampton Town | - | Lincoln City | 0:4 | ||||
| 22. Round | 02/01/2021 | Northampton Town | - | Sunderland AFC | 0:0 |
England