| 1. Round | 20/09/2020 | RB Leipzig | - | 1. FSV Mainz 05 | 3:1 | ||||
| 2. Round | 26/09/2020 | Bayer Leverkusen | - | RB Leipzig | 1:1 | ||||
| 4. Round | 17/10/2020 | FC Augsburg | - | RB Leipzig | 0:2 | ||||
| 6. Round | 31/10/2020 | Bor. Mönchengladbach | - | RB Leipzig | 1:0 |  |
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| 7. Round | 07/11/2020 | RB Leipzig | - | SC Freiburg | 3:0 | ||||
| 15. Round | 09/01/2021 | RB Leipzig | - | Borussia Dortmund | 1:3 | ||||
| 18. Round | 23/01/2021 | 1. FSV Mainz 05 | - | RB Leipzig | 3:2 | ||||
| 20. Round | 06/02/2021 | FC Schalke 04 | - | RB Leipzig | 0:3 | ||||
| 22. Round | 21/02/2021 | Hertha BSC | - | RB Leipzig | 0:3 | ||||
| 24. Round | 06/03/2021 | SC Freiburg | - | RB Leipzig | 0:3 | |
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| 25. Round | 14/03/2021 | RB Leipzig | - | Eintracht Frankfurt | 1:1 | ||||
| 26. Round | 19/03/2021 | Arminia Bielefeld | - | RB Leipzig | 0:1 | ||||
| 27. Round | 03/04/2021 | RB Leipzig | - | Bayern München | 0:1 | ||||
| 28. Round | 10/04/2021 | Werder Bremen | - | RB Leipzig | 1:4 | ||||
| 30. Round | 20/04/2021 | 1. FC Köln | - | RB Leipzig | 2:1 | ||||
| 32. Round | 08/05/2021 | Borussia Dortmund | - | RB Leipzig | 3:2 | ||||
| 33. Round | 16/05/2021 | RB Leipzig | - | VfL Wolfsburg | 2:2 | ||||
| 34. Round | 22/05/2021 | 1. FC Union Berlin | - | RB Leipzig | 2:1 |
South Korea
