| 5. Round | 24/10/2020 | RB Leipzig | - | Hertha BSC | 2:1 | ||||
| 7. Round | 07/11/2020 | RB Leipzig | - | SC Freiburg | 3:0 |  |
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| 8. Round | 21/11/2020 | Eintracht Frankfurt | - | RB Leipzig | 1:1 | ||||
| 9. Round | 28/11/2020 | RB Leipzig | - | Arminia Bielefeld | 2:1 | ||||
| 10. Round | 05/12/2020 | Bayern München | - | RB Leipzig | 3:3 | ||||
| 12. Round | 16/12/2020 | 1899 Hoffenheim | - | RB Leipzig | 0:1 | ||||
| 21. Round | 12/02/2021 | RB Leipzig | - | FC Augsburg | 2:1 | ||||
| 22. Round | 21/02/2021 | Hertha BSC | - | RB Leipzig | 0:3 | ||||
| 24. Round | 06/03/2021 | SC Freiburg | - | RB Leipzig | 0:3 | ||||
| 27. Round | 03/04/2021 | RB Leipzig | - | Bayern München | 0:1 | ||||
| 28. Round | 10/04/2021 | Werder Bremen | - | RB Leipzig | 1:4 | ||||
| 29. Round | 16/04/2021 | RB Leipzig | - | 1899 Hoffenheim | 0:0 | ||||
| 31. Round | 25/04/2021 | RB Leipzig | - | VfB Stuttgart | 2:0 |  |
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| 33. Round | 16/05/2021 | RB Leipzig | - | VfL Wolfsburg | 2:2 | |
France
Mali 
