| 3. Round | 17/08/2021 | Reading FC | - | Bristol City | 2:3 | ||||
| 4. Round | 21/08/2021 | Coventry City | - | Reading FC | 2:1 |  |
|||
| 5. Round | 28/08/2021 | Huddersfield Town | - | Reading FC | 4:0 | ||||
| 10. Round | 29/09/2021 | Derby County | - | Reading FC | 1:0 | ||||
| 11. Round | 02/10/2021 | Cardiff City | - | Reading FC | 0:1 | ||||
| 13. Round | 20/10/2021 | Reading FC | - | Blackpool FC | 2:3 | ||||
| 14. Round | 23/10/2021 | Blackburn Rovers | - | Reading FC | 2:0 | ||||
| 15. Round | 30/10/2021 | Reading FC | - | AFC Bournemouth | 0:2 | ||||
| 16. Round | 02/11/2021 | Millwall FC | - | Reading FC | 1:0 | ||||
| 17. Round | 06/11/2021 | Birmingham City | - | Reading FC | 1:2 |  |
|||
| 23. Round | 19/01/2022 | Reading FC | - | Luton Town | 0:2 | ||||
| 28. Round | 22/01/2022 | Reading FC | - | Huddersfield Town | 3:4 |
England