| 1. Round | 07/08/2010 | Exeter City | - | Colchester United | 2:2 | ||||
| 4. Round | 28/08/2010 | Leyton Orient | - | Exeter City | 3:0 | ||||
| 2. Round | 21/09/2010 | Dagenham & Redbridge | - | Exeter City | 1:1 | ||||
| 9. Round | 28/09/2010 | AFC Bournemouth | - | Exeter City | 3:0 | ||||
| 13. Round | 23/10/2010 | Milton Keynes Dons | - | Exeter City | 1:0 | ||||
| 14. Round | 30/10/2010 | Exeter City | - | Brentford FC | 2:4 | ||||
| 21. Round | 18/12/2010 | Exeter City | - | Sheffield Wednesday | 5:1 | ||||
| 24. Round | 01/01/2011 | Southampton FC | - | Exeter City | 4:0 | ||||
| 27. Round | 14/01/2011 | Brentford FC | - | Exeter City | 1:1 | ||||
| 29. Round | 29/01/2011 | Swindon Town | - | Exeter City | 0:0 | ||||
| 31. Round | 05/02/2011 | Exeter City | - | Huddersfield Town | 1:4 | ||||
| 40. Round | 02/04/2011 | Exeter City | - | Dagenham & Redbridge | 2:1 | ||||
| 41. Round | 09/04/2011 | Bristol Rovers | - | Exeter City | 0:2 | ||||
| 42. Round | 16/04/2011 | Exeter City | - | Leyton Orient | 2:1 | ||||
| 43. Round | 22/04/2011 | Exeter City | - | Oldham Athletic | 2:0 | ||||
| 44. Round | 25/04/2011 | Tranmere Rovers | - | Exeter City | 4:0 |
England