| 1. Round | 07/08/2021 | Wycombe Wanderers | - | Accrington Stanley | 2:1 | ||||
| 2. Round | 14/08/2021 | Accrington Stanley | - | Cambridge United | 2:1 |  |
|||
| 3. Round | 17/08/2021 | Accrington Stanley | - | Doncaster Rovers | 1:0 | ||||
| 4. Round | 21/08/2021 | Crewe Alexandra | - | Accrington Stanley | 0:1 | ||||
| 40. Round | 26/03/2022 | Accrington Stanley | - | Gillingham FC | 1:2 | ||||
| 41. Round | 02/04/2022 | Accrington Stanley | - | Cheltenham Town | 4:4 | ||||
| 26. Round | 05/04/2022 | Wigan Athletic | - | Accrington Stanley | 3:0 | ||||
| 42. Round | 09/04/2022 | Fleetwood Town | - | Accrington Stanley | 1:2 | ||||
| 43. Round | 15/04/2022 | Accrington Stanley | - | Burton Albion | 0:0 | ||||
| 44. Round | 18/04/2022 | Bolton Wanderers | - | Accrington Stanley | 3:1 |
England