| Group G | 15/09/2016 | Panathinaikos | - | AFC Ajax | 1:2 |  |
|||
| Group G | 29/09/2016 | AFC Ajax | - | Standard Liège | 1:0 | ||||
| Group G | 20/10/2016 | RC Celta | - | AFC Ajax | 2:2 | |
|||
| Group G | 03/11/2016 | AFC Ajax | - | RC Celta | 3:2 | ||||
| Round of 32 | 23/02/2017 | AFC Ajax | - | Legia Warszawa | 1:0 | |
|||
| Round of 16 | 16/03/2017 | AFC Ajax | - | FC København | 2:0 | ||||
| Quarter-finals | 13/04/2017 | AFC Ajax | - | FC Schalke 04 | 2:0 | ||||
| Quarter-finals | 20/04/2017 | FC Schalke 04 | - | AFC Ajax | 3:2 aet |  |
|||
| Semi-finals | 11/05/2017 | Olympique Lyonnais | - | AFC Ajax | 3:1 | |
|||
| Final | 24/05/2017 | AFC Ajax | - | Manchester United | 0:2 | |
Netherlands