| 1. Round | 27/08/1921 | Blackburn Rovers | - | Chelsea FC | 1:1 | ||||
| 2. Round | 29/08/1921 | Bradford City | - | Blackburn Rovers | 1:1 |  |
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| 3. Round | 03/09/1921 | Chelsea FC | - | Blackburn Rovers | 1:0 | ||||
| 5. Round | 10/09/1921 | West Bromwich Albion | - | Blackburn Rovers | 0:2 | |
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| 36. Round | 12/09/1921 | Aston Villa | - | Blackburn Rovers | 1:1 | ||||
| 6. Round | 17/09/1921 | Blackburn Rovers | - | West Bromwich Albion | 2:3 | ||||
| 4. Round | 19/09/1921 | Blackburn Rovers | - | Bradford City | 3:1 | |
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| 7. Round | 24/09/1921 | Manchester City | - | Blackburn Rovers | 1:1 | ||||
| 8. Round | 01/10/1921 | Blackburn Rovers | - | Manchester City | 3:1 | ||||
| 9. Round | 08/10/1921 | Everton FC | - | Blackburn Rovers | 2:0 | ||||
| 10. Round | 15/10/1921 | Blackburn Rovers | - | Everton FC | 2:2 | ||||
| 11. Round | 22/10/1921 | Sunderland AFC | - | Blackburn Rovers | 3:1 | ||||
| 12. Round | 29/10/1921 | Blackburn Rovers | - | Sunderland AFC | 1:2 | ||||
| 15. Round | 19/11/1921 | Blackburn Rovers | - | Birmingham FC | 1:1 | ||||
| 16. Round | 26/11/1921 | Birmingham FC | - | Blackburn Rovers | 1:0 | ||||
| 35. Round | 01/04/1922 | Blackburn Rovers | - | Aston Villa | 1:2 |
Scotland