| 2. Round | 14/08/2021 | Oxford United | - | Charlton Athletic | 2:1 | ||||
| 3. Round | 17/08/2021 | Oxford United | - | Crewe Alexandra | 1:0 | ||||
| 29. Round | 22/01/2022 | Oxford United | - | Sheffield Wednesday | 3:2 | ||||
| 18. Round | 01/02/2022 | Wigan Athletic | - | Oxford United | 1:1 | ||||
| 31. Round | 05/02/2022 | Oxford United | - | Portsmouth FC | 3:2 | ||||
| 38. Round | 12/03/2022 | Shrewsbury Town | - | Oxford United | 1:2 |
England
Portugal 