| 1. Round | 06/08/2011 | Rotherham United | - | Oxford United | 1:0 | ||||
| 2. Round | 13/08/2011 | Oxford United | - | Bradford City | 1:1 |  |
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| 5. Round | 27/08/2011 | Oxford United | - | Aldershot Town | 1:1 | ||||
| 6. Round | 03/09/2011 | Crewe Alexandra | - | Oxford United | 3:1 | ||||
| 7. Round | 10/09/2011 | Oxford United | - | Burton Albion | 2:2 | ||||
| 23. Round | 31/12/2011 | Torquay United | - | Oxford United | 0:0 | ||||
| 24. Round | 02/01/2012 | Oxford United | - | Crawley Town | 1:1 |  |
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| 25. Round | 07/01/2012 | Aldershot Town | - | Oxford United | 0:3 | |
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| 26. Round | 14/01/2012 | Oxford United | - | Crewe Alexandra | 0:1 | ||||
| 27. Round | 21/01/2012 | Oxford United | - | Hereford United | 2:2 | |
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| 28. Round | 29/01/2012 | Burton Albion | - | Oxford United | 1:1 | ||||
| 34. Round | 03/03/2012 | Oxford United | - | Swindon Town | 2:0 | ||||
| 41. Round | 06/04/2012 | Northampton Town | - | Oxford United | 2:1 | ||||
| 45. Round | 28/04/2012 | Oxford United | - | Southend United | 0:2 | ||||
| 46. Round | 05/05/2012 | Port Vale FC | - | Oxford United | 3:0 | |
USA