| 28. Round | 23/01/2016 | Portsmouth FC | - | Oxford United | 0:1 |  |
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| 26. Round | 09/02/2016 | Oxford United | - | Mansfield Town | 2:2 | ||||
| 31. Round | 13/02/2016 | Morecambe FC | - | Oxford United | 2:4 | |
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| 29. Round | 16/02/2016 | Oxford United | - | Northampton Town | 0:1 | ||||
| 32. Round | 20/02/2016 | Oxford United | - | Accrington Stanley | 1:2 | ||||
| 30. Round | 23/02/2016 | Exeter City | - | Oxford United | 1:4 | |
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| 33. Round | 27/02/2016 | AFC Wimbledon | - | Oxford United | 1:2 | |
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| 34. Round | 01/03/2016 | Oxford United | - | York City | 4:0 | |
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| 35. Round | 05/03/2016 | Plymouth Argyle | - | Oxford United | 2:2 | ||||
| 36. Round | 12/03/2016 | Oxford United | - | Leyton Orient | 0:1 | ||||
| 37. Round | 19/03/2016 | Barnet FC | - | Oxford United | 0:3 | ||||
| 38. Round | 25/03/2016 | Oxford United | - | Stevenage FC | 1:1 | ||||
| 39. Round | 28/03/2016 | Cambridge United | - | Oxford United | 0:0 | ||||
| 42. Round | 16/04/2016 | Oxford United | - | Luton Town | 2:3 | ||||
| 43. Round | 19/04/2016 | Newport County | - | Oxford United | 1:1 | |
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| 45. Round | 30/04/2016 | Carlisle United | - | Oxford United | 0:2 | ||||
| 46. Round | 07/05/2016 | Oxford United | - | Wycombe Wanderers | 3:0 |
England
