| 2. Round | 19/09/2020 | Crawley Town | - | Scunthorpe United | 1:0 | ||||
| 3. Round | 26/09/2020 | Scunthorpe United | - | Carlisle United | 1:0 |  |
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| 13. Round | 21/11/2020 | Scunthorpe United | - | Morecambe FC | 1:1 | ||||
| 14. Round | 24/11/2020 | Scunthorpe United | - | Bolton Wanderers | 0:1 | ||||
| 17. Round | 12/12/2020 | Southend United | - | Scunthorpe United | 1:0 | ||||
| 18. Round | 15/12/2020 | Scunthorpe United | - | Barrow AFC | 2:1 | ||||
| 25. Round | 23/01/2021 | Scunthorpe United | - | Grimsby Town | 3:0 | ||||
| 30. Round | 20/02/2021 | Scunthorpe United | - | Harrogate Town | 3:1 | ||||
| 32. Round | 27/02/2021 | Scunthorpe United | - | Cheltenham Town | 0:2 | ||||
| 34. Round | 06/03/2021 | Salford City | - | Scunthorpe United | 1:1 | ||||
| 35. Round | 09/03/2021 | Scunthorpe United | - | Exeter City | 0:2 | ||||
| 36. Round | 13/03/2021 | Leyton Orient | - | Scunthorpe United | 1:1 | ||||
| 28. Round | 16/03/2021 | Scunthorpe United | - | Oldham Athletic | 1:1 | |
England