| 1. Round | 07/11/2021 | Sheffield Wednesday | - | Plymouth Argyle | 0:0 | ||||
| 1. Round | 16/11/2021 | Plymouth Argyle | - | Sheffield Wednesday | 3:0 |  |
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| 2. Round | 05/12/2021 | Rochdale AFC | - | Plymouth Argyle | 1:2 | |
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| 3. Round | 08/01/2022 | Birmingham City | - | Plymouth Argyle | 0:1 aet | ||||
| 4. Round | 05/02/2022 | Chelsea FC | - | Plymouth Argyle | 2:1 aet |
Jamaica
England