| 9. Round | 26/09/2021 | CSKA Sofia | - | Levski Sofia | 2:1 | ||||
| 12. Round | 23/10/2021 | Levski Sofia | - | Pirin Blagoevgrad | 3:0 | ||||
| 13. Round | 30/10/2021 | Cherno More Varna | - | Levski Sofia | 1:0 | ||||
| 14. Round | 06/11/2021 | Slavia Sofia | - | Levski Sofia | 0:1 |  |
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| 15. Round | 22/11/2021 | Levski Sofia | - | Botev Vratsa | 0:0 | ||||
| 16. Round | 27/11/2021 | Arda Kardzhali | - | Levski Sofia | 0:0 | |
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| 17. Round | 01/12/2021 | Tsarsko Selo Sofia | - | Levski Sofia | 0:1 | |
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| 18. Round | 04/12/2021 | Levski Sofia | - | Botev Plovdiv | 2:0 | ||||
| 19. Round | 12/12/2021 | PFC Beroe | - | Levski Sofia | 1:1 | ||||
| 20. Round | 19/02/2022 | Levski Sofia | - | Lokomotiv Plovdiv | 2:1 | ||||
| 21. Round | 26/02/2022 | CSKA 1948 Sofia | - | Levski Sofia | 0:2 | |
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| 22. Round | 06/03/2022 | Levski Sofia | - | CSKA Sofia | 0:0 | ||||
| 23. Round | 13/03/2022 | PFC Ludogorets Razgrad | - | Levski Sofia | 2:1 | ||||
| 24. Round | 19/03/2022 | Levski Sofia | - | Lokomotiv Sofia | 1:0 | ||||
| 25. Round | 03/04/2022 | Pirin Blagoevgrad | - | Levski Sofia | 0:3 | ||||
| 26. Round | 09/04/2022 | Levski Sofia | - | Cherno More Varna | 2:0 |
Panama